There's something quietly satisfying about routing New Mexico's high-desert light toward the Cycladic sun, and doing it properly means booking business class from Albuquerque to Santorini through one of Europe's legacy hubs rather than hunting for a mythical nonstop that doesn't exist. Since JTR has no long-haul widebody service, the real work happens on the transatlantic leg: connect via London on British Airways or via Frankfurt/Munich on Lufthansa, then finish on an Aegean Airlines short-hop into Santorini's small, seasonal airport. Fact for the record: total journey time from ABQ to JTR runs roughly 13 hours of flying, though with connections you should budget closer to 16-18 hours door to door given the ABQ-to-hub positioning segment.
My preference, after flying this corridor several times, is the British Airways routing through London Heathrow, where the Club Suite on the 777 or A350 gives you direct aisle access and a proper door — a meaningful upgrade over BA's older Club World cabins still flying on some Boeing 787s, so it's worth checking your aircraft type at booking. Lufthansa's newer Allegris business seats are excellent when you can get them, but the rollout is uneven across the fleet, so verify the specific aircraft before counting on it for the Frankfurt or Munich leg. Whichever hub you choose, the final Aegean Airlines segment to Santorini is a modest regional cabin — treat it as a scenic descent rather than part of the luxury experience, and try to snag a window seat on the left side for the caldera approach. Insider tip: fly into Santorini before 2pm if possible, since afternoon meltemi winds can cause delays and even diversions to Athens during peak summer months.
Shoulder season — April, May, September, and October — is when this route rewards patience, both for calmer winds over the caldera and softer business class award and cash pricing across all three carriers. Because fares on this itinerary swing with hub competition and Aegean's limited seasonal schedule, setting up automated fare alerts is genuinely the smartest way to catch the right combination before it disappears.