There's no nonstop between BWI and BFS, and that single fact shapes every good routing decision on this itinerary: business class from Baltimore to Belfast requires a connection, typically through Philadelphia or Charlotte on American, JFK or Boston on Delta, or London Heathrow on British Airways. Having flown all three permutations, my strong preference is the BA option via Heathrow, where the Club Suite—with its sliding door and direct aisle access on the 777 and A350 fleets—makes the transatlantic leg feel like a genuine flat-bed retreat rather than a recliner with a curtain. The Belfast leg on BA is typically a short A320 or A321neo hop in Club Europe, which is a modest downgrade but tolerable given the brevity.
American's routing through Charlotte or Philadelphia gets you into their Flagship Business suites on the long-haul segment (777-300ER or 787-9, depending on rotation), with forward-facing pods and reliable Wi-Fi, but the domestic connection adds friction that BA's single-carrier itinerary avoids. Delta's JFK or Boston connections put you into Delta One suites with sliding doors, and Delta's operational reliability into Heathrow or a European gateway before the final Belfast hop is genuinely strong, especially in shoulder season. My insider tip: if routing through Heathrow on BA, aim for a same-terminal connection (T5 to T5 domestic-style transfers to Belfast) rather than the T3-to-T5 shuffle that some fare classes default you into—call and confirm terminal assignment before ticketing, since this alone can save 40 minutes of stress.
Seasonally, January through March and again in October and November are when premium fares on this US-to-UK corridor loosen up, as Belfast's tourism surges are concentrated in summer and around St. Patrick's Day travel from the diaspora crowd. Given how thinly these connections are scheduled, and how quickly award and discounted business fares disappear on the BWI–Belfast corridor, setting up automated fare alerts is the smartest move you can make before booking.