There's no nonstop path connecting Detroit to Faro, which means the real decision on this route isn't whether to fly business class but which European gateway makes the connection sing. As it stands, business class from Detroit to Faro requires a routing through Amsterdam, Paris, London, or Lisbon, since Delta, TAP Air Portugal, and British Airways all serve the Algarve via their respective hubs rather than direct metal from the Motor City. My preferred combination, after years of testing this itinerary each shoulder season, pairs Delta's transatlantic business class out of DTW (Delta One, either the older reverse-herringbone suite or the newer Delta One Suite with sliding door, depending on aircraft assignment) with a TAP Air Portugal narrowbody business connection into Faro from Lisbon — TAP's A321 business cabins are simple but efficient, and Lisbon's connections to Faro are frequent enough that a two-hour buffer rarely turns into stress.
British Airways offers an alternative worth considering if your dates favor a London connection: Club Suite on the transatlantic leg from a BA-operated JFK or ORD routing (Detroit doesn't get BA metal directly, so you'd position through a codeshare or separate Delta segment first), followed by a short business hop from Heathrow into Faro on BA's seasonal summer service. My insider tip: book the TAP or BA connection with enough runway at Lisbon or Heathrow that you can use the lounge shower facilities before the final short hop — landing in the Algarve fresh, rather than rumpled from an overnight transatlantic flight, sets the tone for the whole trip, and few travelers plan for that middle segment properly.
April, May, September, and October remain the sweet spot for this routing, both for weather in the Algarve and for softer premium-cabin demand across all three carriers. Because award and revenue business fares on this multi-carrier itinerary fluctuate with connection availability rather than pure seasonality, setting up automated fare tracking for the DTW–FAO corridor is the smartest move you can make before committing to dates.