Southwest Florida's snowbird crowd has long treated Gran Canaria as a well-kept secret, but getting there in proper comfort requires a bit of routing savvy since no carrier flies nonstop between RSW and the Canary Islands. There is no business class from Fort Myers to Gran Canaria on a single-ticket nonstop basis; instead, the smart play runs through Madrid or London, with Iberia, British Airways, and Lufthansa all offering viable connections and roughly nine hours of total flight time once you account for the transatlantic leg. Iberia's Madrid hub is the most elegant solution for this itinerary, since IB operates frequent A320-family flights from MAD to LPA and their long-haul A330/A350 business class from the US brings flat-bed seating and a genuinely Spanish culinary experience that primes you for the Canaries.
Having routed through both London and Madrid on trips to LPA, I'd steer seasoned travelers toward the Iberia-via-Madrid connection over British Airways' Heathrow routing, simply because Terminal 4 at MAD is purpose-built for this kind of transfer, with minimal walking between Iberia's long-haul arrivals and their domestic-style departures to the islands — a far gentler experience than the sprawl of LHR Terminal 5, even with BA's well-regarded Club Suite offering direct-aisle access and doors on their 777s and A350s. Lufthansa's alternative, routing through Frankfurt with their newer Allegris cabin on select long-haul aircraft, appeals if you're layering in a Central European stopover, but the Frankfurt-to-Canaries connection times can be tighter than ideal, so I'd only recommend LH if you're comfortable building in extra buffer or an overnight break. One insider tip few mention: flying into LPA in the late afternoon lets you clear the compact arrivals hall before the wave of intra-European charter flights hits, which can otherwise create unexpected queues at passport control.
April, May, September, and October consistently offer the best value and calmer winds for this route, as the winter high season sees Northern Europeans flood the islands and push fares upward across all three carriers. Given the multi-carrier, multi-hub nature of this journey, fares can shift quickly depending on which connection opens up award or discounted business inventory first, so setting fare alerts across Iberia, British Airways, and Lufthansa is the most reliable way to catch a premium seat to Gran Canaria without overpaying.