There's no shortage of ways to get from Southwest Florida to Yorkshire, but anyone who's done this journey repeatedly knows the truth: there's no realistic path to business class from Fort Myers to Leeds without a connection, since Leeds Bradford Airport simply doesn't handle widebody transatlantic traffic. The honest answer is that RSW to LBA business class travel means routing through a major East Coast or European hub, with Delta, American, and United all offering one-stop itineraries via their respective gateways—Delta through JFK or Atlanta with onward partner service, American via Philadelphia or their transatlantic joint venture cities, and United through Newark, all connecting onward to Leeds via a partner carrier's short-haul business cabin, since none of the three US majors fly the LBA sector themselves.
Having flown this corridor numerous times, I've found the sweet spot is a Delta routing through JFK, where you can enjoy Delta One suites (with the sliding door, on A330-900 or A350 equipped flights) across the Atlantic before a short partner hop up to Yorkshire. American's transatlantic business product, Flagship Suite on select 777 and A321XLR aircraft, is another strong option if your positioning flight aligns well through Philadelphia, while United's Polaris seats out of Newark remain a dependable choice, particularly on the 767 and 777 fleet. My insider tip: build in at least a 2.5-hour connection window at JFK or Newark during winter months, since de-icing delays on both the transatlantic and short domestic legs are common January through March and can cascade quickly if you cut it close.
The shoulder seasons—January, February, March, and again in October and November—consistently deliver the softest business class fares on this corridor, as Florida's peak snowbird season creates demand imbalances that smart pricing algorithms exploit in the opposite direction on connecting legs. Given the complexity of pricing a three-carrier, multi-hub route like this, I'd strongly recommend setting up automated fare alerts rather than manually checking, since the best award and cash fares on this itinerary tend to appear briefly before disappearing within days.