Few routings in global aviation demand as much strategic patience as the journey from Honolulu to Zagreb business class, a pairing that stitches together Pacific volcanic air with Adriatic limestone via at least two continents. There is no nonstop option, and there never will be one anytime soon, so the real decision isn't whether to connect but where. Delta passengers typically route through Atlanta or Los Angeles into a transatlantic gateway, while the more elegant path leans on Lufthansa's strength through Frankfurt or Munich, connecting onward to Zagreb on a short Star Alliance hop, sometimes operated by Croatia Airlines (OU) itself. I've found that Munich offers a calmer connection than Frankfurt during peak European summer congestion, with shorter walks between arriving long-haul flights and the compact regional gates used for Zagreb departures.
The heart of this journey is the transpacific-to-transatlantic combination, and Lufthansa's widebody fleet is where the comfort case is made. Depending on aircraft assignment, you may find yourself in Lufthansa's newer Allegris business suites with sliding doors on select 787 and A350 routes, though older 747-8 and A340 configurations with the earlier lie-flat business seat still appear on many Frankfurt and Munich pairings, so it's worth checking your specific aircraft before booking. Delta's transpacific legs out of Honolulu, often via Los Angeles or Seattle, bring Delta One suites into play, a genuine door-equipped lie-flat product that makes the first several hours of this marathon far more restorative than the standard recliner seats you'd find on older widebodies.
Seasonality rewards the patient traveler here: January through March and again in October and November tend to open the widest award and premium cash availability, since Croatian leisure demand collapses outside summer and Hawaii-Europe traffic thins in tandem. My insider tip: search Zagreb availability on Croatia Airlines' own short connecting flights separately from the long-haul award space, as OU segments often free up independently of Lufthansa's transatlantic cabins, unlocking itineraries that appear "sold out" as a single search. Given the volatility across three carriers and multiple hub options, setting continuous fare alerts is the smartest way to catch the inevitable pricing dips on this complex, rewarding route.