Birmingham's compact airport rarely tops the wish list for premium American flyers, but that's precisely what makes this Midlands routing so appealing once you understand the mechanics. There's no nonstop option here: business class from Houston to Birmingham means routing through London, most sensibly via Heathrow, then a short domestic hop or rail connection into the UK's second city. United flies IAH-LHR nonstop on its 787 or 777 fleet, offering Polaris seating with direct aisle access and proper lie-flat privacy, while American and British Airways route through their own webs—American via its Heathrow codeshare with BA, and British Airways offering its own IAH-LHR service (seasonally) or connections through Dallas or JFK. I've flown this corridor enough times to know the real decision isn't which airline, but which connection minimizes your Heathrow dwell time, since T5 to T3 transfers (if you land BA and connect BA) are far smoother than crossing to a different terminal for a partner carrier.
My strongest recommendation: if British Airways is operating, seek out their Club Suite product, now rolling out across more of the fleet—it's a genuine step up from the older Club World cabin, with a proper door and forward-facing bed. United's Polaris remains the more consistent bet on the transatlantic leg itself, particularly on 777-300ER aircraft with the newest cabin retrofit. Whichever airline you choose, build in at least a two-hour connection at Heathrow; even with priority disembarkation, immigration and terminal transfers eat time fast, and missing your Birmingham connector means waiting hours for the next slot, since BHX frequency from LHR is limited to a handful of daily flights.
Winter and shoulder seasons—January through March, then October and November—consistently offer the softest business fares on this corridor, as Houston's energy-sector business travel dips and UK leisure demand hasn't yet surged. Business travelers heading to Birmingham's manufacturing and automotive sector meetings should also note that fare volatility on this route is unusually sharp given the limited nonstop competition, so setting up automated fare alerts is the smartest way to catch a premium seat before prices reset.