Reykjavík rewards patience, and after a dozen crossings on this circuitous itinerary, I've learned that there's no nonstop shortcut from Northeast Florida to Iceland's volcanic coastline. Booking business class from Jacksonville to Reykjavík requires a connection, and the truth is that's actually a feature, not a bug: Delta's hub in Atlanta or JFK, and United's Newark and Dulles gateways, both allow you to transfer onto widebody metal with legitimate lie-flat business seating for the transatlantic leg, rather than the narrower regional jets that would otherwise dominate a direct-if-it-existed routing. Icelandair, meanwhile, operates Saga Class on its 757s and 737 MAX aircraft out of several East Coast cities, though Jacksonville isn't currently one of their direct-service markets, so most travelers I know route through Boston or JFK to catch Icelandair's own product, which leans more premium-economy-plus than true flat-bed but comes with Icelandair's famous free stopover policy in Keflavík.
The real strategic decision is which connecting hub rewards you with the best hard product for the long transatlantic hop. Delta's One Suites, when scheduled on the JFK or Atlanta departure, deliver sliding doors and genuine privacy that make the six-plus-hour crossing feel civilized, while United's Polaris seats out of Newark or Dulles offer similarly enclosed suites with good storage for the overnight arrival into KEF's compact single-terminal airport, where immigration typically moves fast even during peak summer congestion. My insider tip: land at Keflavík between 6 and 8 a.m., which is when most transatlantic red-eyes converge, then head straight for the Blue Lagoon before your hotel check-in time — the crowds there thin dramatically before 9 a.m., something most guides won't tell you.
Iceland's short, intense tourist season means late spring through early autumn — May through September — consistently produces the most favorable business class fares and the widest seasonal schedules from all three carriers, as airlines add frequencies to meet demand for the midnight sun. Because fare movement on this Jacksonville–Reykjavík corridor can be erratic given the connection variables, setting up automated price tracking is the smartest way to catch a premium-cabin deal before it disappears.