Memphis isn't a city that offers nonstop access to the Dalmatian coast, so anyone booking business class from Memphis to Split needs to think strategically about connections rather than routing. The reality: there is no direct service, and the most reliable path routes through a major Delta, American, or United gateway before crossing the Atlantic — Delta via JFK or Atlanta into a European partner hub, American via its Charlotte or Philadelphia gateways with a transatlantic leg on a joint-venture partner, or United via its Newark hub, all connecting onward to Split via a secondary European city like Frankfurt, Munich, or Zurich, since Split's airport doesn't support widebody long-haul arrivals. Total journey time typically runs 14-16 hours door-to-door once you factor in the connection, even though the core transatlantic segment clocks in around 11.5 hours.
Having routed this trip more times than I can count, my strong preference is Delta through JFK, where the lounge access and boarding priority make the layover feel less like a chore — Delta One's suite product on transatlantic widebodies (777s and A330s/A350s depending on the specific pairing) offers a proper flat bed and door, which matters enormously on an overnight crossing before you tackle a same-day European connector. American passengers should look at Philadelphia connections onto British Airways or Finnair metal for the European leg, both of which run reliable narrow- or widebody service into secondary Adriatic gateways. One insider tip: build in a 3+ hour connection window in your European hub city regardless of carrier, because Split's arrival slots are seasonal and tight in peak summer, and missing a rebooking window there can strand you for a full day given limited daily frequencies.
Shoulder season — April, May, September, and October — consistently delivers the best business class value on this routing, both because Croatian coastal demand drops and transatlantic capacity into Europe remains robust. Given the multiple carrier and routing combinations at play, setting up automated fare alerts for this specific city pair is the smartest way to catch a premium cabin seat before it disappears.