Alicante's Costa Blanca charm doesn't come with a nonstop lifeline from Music City, which is exactly why routing strategy matters more here than on most transatlantic pairings. There is no direct business class from Nashville to Alicante, so the real decision is which one-stop itinerary delivers the best hard product for the roughly ten-hour cumulative journey. American Airlines passengers typically connect through Charlotte, Philadelphia, or Chicago before crossing the Atlantic, but the more rewarding play is routing via London or Madrid on American's joint-venture partners British Airways and Iberia, both of which touch Alicante or offer easy onward connections. British Airways' Club Suite, with its sliding door and direct aisle access, is worth angling for on the transatlantic leg out of Heathrow, while Iberia's A330 and A350 business cabins—lie-flat with reasonable width—cover the Madrid-to-Alicante or Madrid-origin segments nicely.
Having flown this corridor several times, my preference is funneling through Madrid rather than London whenever schedules allow. Iberia's Terminal 4 at Barajas is efficient, immigration for EU arrivals moves quickly, and the short domestic-style hop down to Alicante feels almost like an afterthought compared to the long-haul crossing. One insider tip that rarely gets mentioned: Iberia occasionally releases better business award and revenue space on the Madrid-Alicante short-haul segment as a standalone booking-in-conjunction fare, which can unlock a lie-flat transatlantic seat that wouldn't otherwise show as available when searched as a single itinerary from BNA.
Seasonality plays heavily in your favor if you're flexible. April, May, September, and October consistently produce the strongest business class value on this US-to-Spain corridor, avoiding both the summer peak crowds funneling into the Costa Blanca and the deep winter lull when schedules thin out. Given the volatility in premium fares on these connecting itineraries, setting up automated fare alerts for the Nashville-Alicante corridor is the smartest way to catch these seasonal dips before they disappear.