There's no nonstop route between John Wayne Airport and Birmingham, England, so booking business class from Orange County to Birmingham means threading together SNA's tight departure schedule with a strategic transatlantic connection, and after a couple dozen crossings I've settled firmly on routing through the carriers' domestic hubs rather than fighting the geography. American, Delta, and United all serve this corridor via their own connecting cities—American through Charlotte or Philadelphia into London Heathrow, Delta through Atlanta or JFK into Heathrow or Amsterdam-style European gateways, and United through its Newark or Chicago hub—before you take a short onward hop or train into Birmingham itself, since none of the majors fly SNA-BHX direct or even BHX at all from the US mainland. The honest factual answer: expect a total journey of roughly 13-15 hours including one connection, with the long-haul segment clocking in near 10 hours in the air.
What separates a great business class experience here from a mediocre one is the transatlantic hard product you land on your connecting hub, not the SNA departure itself, which is a short regional hop in a narrowbody first-class cabin. American's Flagship Business on its 777 or 787 gives you a proper lie-flat suite with direct aisle access on the 777; Delta's One Suites on the A350 or 767 are similarly excellent, especially out of JFK; United's Polaris seats on 777-300ERs from Newark or Chicago round out the trio nicely. My insider tip: fly the SNA connection as early as possible in the morning—John Wayne's noise curfew means late flights get cancelled or delayed more often than travelers expect, and missing a tight connection to a transatlantic business seat is a costly mistake.
January through March and again in October and November are consistently the softest months for fares on this corridor, as Birmingham-bound leisure demand dips outside summer festivals and Christmas markets. Given how much these fares swing hub-to-hub and week-to-week, setting up automated fare alerts for this specific SNA-BHX business class routing is the smartest move you can make before booking.