There's no nonstop lifeline linking Orlando to the Costa Blanca, which means every itinerary in business class from Orlando to Alicante runs through a European or East Coast gateway, and after years of routing this journey I've settled on a firm conclusion: London remains the smartest connection. British Airways operates the strongest single-carrier option, funneling MCO passengers through Heathrow's Terminal 5 aboard aircraft fitted with the Club Suite—their reverse-herringbone product with a closing door, now standard on many long-haul 777 and A350 rotations from Orlando. American Airlines codeshares extensively with both BA and Iberia through the Oneworld alliance, so loyalists can credit miles accordingly while choosing whichever transatlantic segment offers the better seat that day.
Iberia deserves real consideration too, particularly if your itinerary connects through Madrid rather than London. Iberia's A330 and A350 business cabins, featuring their newer flatbed seats with direct aisle access on the A350s, make for a more relaxed final push into Alicante, since Madrid-to-ALC hops are short and frequent. My own preference on this specific corridor is a Madrid connection whenever schedules allow—immigration and customs in Spain tend to move faster than the sometimes-congested Heathrow transfer process, especially during summer's peak crush. One insider trick: book the Iberia flight that lands in Madrid before 11 a.m., since their afternoon ALC departures cluster tightly and give you breathing room without an overnight layover.
Seasonality matters enormously here. April, May, September, and October consistently deliver the best value and the most comfortable flying conditions, avoiding both the sweltering Spanish summer crowds and Orlando's hurricane-season turbulence. Business travelers heading to Alicante for golf, almond-blossom season, or the Costa Blanca's shoulder-season calm should target these windows first. Given how much fares fluctuate on this three-airline, hub-dependent route, setting up automated fare alerts is genuinely the smartest move you can make before committing to a booking window.