There's no nonstop path linking Orlando to Valencia's understated charm, which is precisely why the routing decision matters more than usual on this itinerary. Since no carrier flies MCO-VLC directly, business class from Orlando to Valencia requires a connection, and after many crossings I've settled firmly on routing through Madrid via Iberia or London via British Airways rather than fighting through a US gateway twice. Iberia's one-stop via Madrid is the cleanest option: American Airlines operates the transatlantic leg from Orlando in its Flagship Business cabin (on the aircraft types it deploys on this route, typically Boeing 777 or 787 configurations with fully lie-flat Flagship Suite-style seating on select equipment), then Iberia's short hop down to Valencia keeps the connection simple and within a single alliance, easing baggage and lounge access.
The alternative, funneling through London on British Airways, brings you into their Club Suite product for the long-haul segment if it's operating on the transatlantic sector that day — a genuine upgrade in privacy with its sliding door, though it demands a longer layover at Heathrow, where Terminal 5's Concorde Room makes the wait worthwhile if you can secure entry. My insider tip: build in enough connection time in Madrid (Iberia's home hub) to visit the Iberia VIP lounge in Terminal 4, and if you're transiting on a Oneworld business fare, request a Fast Track slip at the transfer desk — Madrid's passport control lines swell unpredictably in shoulder season.
April, May, September, and October remain the sweet spot for this corridor, when Valencia's Fallas aftermath and the pre-holiday lull thin out both leisure demand and the peak-summer surge from Florida snowbirds heading the other direction. Given how fares on this Orlando-Valencia corridor swing with connection routing and seasonal capacity shifts on the transatlantic legs, setting up automated fare alerts is the smartest way to catch a favorable business class fare before it disappears.