Zadar's Dalmatian coastline rewards patience, and the routing you choose to get there matters as much as the destination itself. There is no nonstop option for business class from Pittsburgh to Zadar, so the itinerary becomes part of the experience: connecting through Frankfurt or Munich on Lufthansa, through Istanbul on Turkish Airlines, or via Zagreb on Croatia Airlines (OU) after a transatlantic hop. Total journey time typically runs close to 13-14 hours including the connection, though the transatlantic segment itself is roughly 10 hours. My preference has long been the Lufthansa routing through Frankfurt, where the long-haul leg from a US gateway (connecting from PIT) can fall on Lufthansa's Allegris business class on newer 787 and A350 configurations, offering direct-aisle access and sliding privacy doors—a meaningful upgrade over the older business product still flying on some legacy aircraft.
Turkish Airlines via Istanbul is the wildcard worth considering seriously. Turkish's widebody business class, with its lie-flat seats and famously generous catering, plus access to the Istanbul Lounge's live cooking stations, makes for a layover that feels like part of the vacation rather than a chore. From Istanbul, the short hop down to Zadar or Zagreb is usually operated with a comfortable regional aircraft, and IST's connections are engineered for efficiency if you keep your layover under two hours. Munich, by contrast, suits travelers who want a quieter, more orderly connection experience, particularly outside peak summer tourist season.
Shoulder months—April, May, September, and October—are when this routing shines, both for weather in Zadar and for award and premium fare availability, since Croatian coastal demand collapses once July and August crowds disperse. My insider tip: check Croatia Airlines' short intra-European business fares separately from the transatlantic ticket, as positioning yourself through Zagreb or Frankfurt a day early on a discounted fare can sometimes beat a single connecting itinerary on cost and comfort. Given the complexity of these connections, setting fare alerts for Pittsburgh to Zadar business class itineraries is the smartest way to catch the shoulder-season sweet spots before they disappear.