Innsbruck's alpine runway is famously tricky for large jets, which is precisely why nobody flies there nonstop from the Carolinas—and why the routing strategy matters more than usual. There is no direct business class from Raleigh to Innsbruck; instead, the smart money routes through Munich, Frankfurt, or Zurich, connecting onto Austrian Airlines, Lufthansa Group partners, or a short regional hop into INN. Delta and United both offer solid transatlantic business product out of RDU—Delta One suites (increasingly the Airbus A330-900 configuration on European rotations) and United's Polaris seats—getting you efficiently to Atlanta, JFK, Newark, or Dulles before the long haul to a European hub. From there, Austrian Airlines, the natural final-leg carrier given Innsbruck's proximity to Vienna and its own alpine heritage, typically operates narrow-body business class on the last segment, which is comfortable but modest compared to the widebody long-haul cabins—set expectations accordingly.
Having routed through Munich and Zurich myself heading into ski season, I'd steer travelers toward the Munich connection when schedules allow: MUC's proximity to Austria means shorter regional legs and Lufthansa's efficient transfer process, even though your longhaul segment will likely still be on Delta or United metal via a codeshare or separate ticketing arrangement. One insider trick: book the transatlantic and final INN leg as separate tickets if award space is scarce on a single itinerary, since Austrian's short regional business fares are often released independently and can be added cheaply once you've secured the expensive long-haul seat. Build in at least a 90-minute connection in Munich or Zurich during winter months, as de-icing delays are common and Innsbruck's weather-dependent approach means afternoon arrivals see fewer disruptions than early morning ones.
January through March and again in October and November are when this routing sees the most favorable business class pricing, largely because ski season demand spikes over December and summer hiking crowds inflate August fares. Given the complexity of connections and the volatility of hub pricing, setting up fare alerts across Delta, United, and Austrian Airlines for this specific city pair is the most reliable way to catch a well-priced business seat before ski season demand tightens availability.