There's a particular satisfaction in engineering a Reno departure into a Mykonos arrival, given that no carrier threads this needle in one hop — the reality is that business class from Reno to Mykonos always involves at least one, usually two, connections, and the routing you choose shapes the entire experience far more than the destination itself. My preferred build is RNO to a domestic gateway, then onward via Frankfurt or Munich on Lufthansa, with a final short hop into Mykonos or Athens on Aegean Airlines. Lufthansa's long-haul segment is where the real product decision lives: depending on aircraft, you'll either land Lufthansa Allegris seating with its direct-aisle access and adjustable privacy panels, or the older but still comfortable fully flat business seat on the 747-8 or A340 — worth checking your equipment before booking, since Allegris is rolling out gradually and not guaranteed on every frame.
British Airways offers the alternative play, connecting through London Heathrow with their Club Suite product — a genuine game-changer with its door and forward-facing fully flat bed, a marked upgrade over BA's older cradle seats. The Heathrow connection demands patience, though; Terminal 5's transfer security can eat 45 minutes on a busy morning, so build in buffer if your onward Aegean flight to Mykonos has a tight window. Aegean itself, while only a regional carrier here, deserves credit for a polished short-haul business cabin and an efficient Athens hub — and flying into Mykonos in shoulder season means avoiding the summer crush entirely, when the tiny JMK airport becomes a bottleneck of charter traffic and delayed bags.
Seasonality is the real lever on this itinerary: April, May, September, and October consistently offer the best combination of fare value and manageable Mykonos crowds, since July and August inflate both prices and airport chaos. My insider tip: price the return leg through Athens rather than direct into JMK on the way home, as Aegean's Athens-Reno-adjacent connections often open up better business award space than the Mykonos-origin fares. Given how much these premium fares fluctuate across three carriers and multiple hub options, setting up automated fare alerts is the smartest way to catch a genuine window before it closes.