Carving a path from the high desert of Nevada to the volcanic coastline of Tenerife requires patience and strategy, since no carrier offers anything close to a direct routing. In practical terms, business class from Reno to Tenerife means piecing together a domestic or transatlantic connection through a major hub before dropping south into the Canary Islands, with total journey time (including connections) often stretching well beyond the roughly 11-hour flying time itself. The three realistic carriers—Iberia, British Airways, and Lufthansa—each route travelers through their home hubs: Madrid, London Heathrow, or Frankfurt/Munich, respectively, before a final short hop to Tenerife South (TFS).
Having flown all three permutations, my strong recommendation is the Iberia routing via Madrid whenever schedules align. Iberia's A330 and A350 business class cabins offer direct-aisle-access seating on the A350, and Madrid-Barajas is simply the most efficient gateway to the Canaries, with frequent same-terminal connections that spare you the long security re-clear you'd face rerouting through Heathrow's Terminal 5 or Frankfurt. British Airways' Club Suite, found on select 777 and A350 aircraft, is worth chasing if your itinerary naturally routes through Heathrow, as the closing door and reverse-herringbone layout rival anything in the sky right now. Lufthansa's newer Allegris business seats are excellent when assigned, but note that not all aircraft on the Frankfurt-Munich network have been retrofitted yet, so it pays to check the specific equipment before booking.
One insider tip: because Tenerife South handles heavy seasonal leisure traffic, arriving mid-morning rather than late afternoon dramatically eases immigration queues, especially in winter high season. April, May, September, and October remain the sweet spot for both fares and weather, avoiding both winter crowds and summer heat on the island. Given the routing complexity and fare volatility across three separate alliances, setting up automated fare alerts is the smartest way to catch a premium seat at its best value.