Richmond's modest little airfield doesn't get you anywhere near Luxembourg without at least one connection, and that's precisely where the strategy for this route gets interesting. There is no nonstop option: every itinerary in business class from Richmond to Luxembourg routes through a major hub, typically Atlanta or New York-JFK on Delta, or Frankfurt and Munich on Lufthansa, with Luxair filling in the final short hop from a European gateway into LUX itself. Delta's transatlantic metal on this corridor usually means Delta One suites out of JFK or Atlanta with sliding doors and lie-flat comfort, while Lufthansa passengers connecting through Frankfurt or Munich can find themselves in either the long-standing Business Class cabin or, increasingly, the newer Allegris seat on select aircraft — worth checking at booking since Allegris isn't yet fleet-wide. My preference after years working this itinerary is routing via Frankfurt: Lufthansa's home hub has a dedicated business class security lane and the First Class Terminal experience (if you're ticketed appropriately) shortens what can otherwise be a frantic connection into a Luxair prop or regional jet to LUX.
The insider move here is booking the Lufthansa-Luxair combination through Frankfurt rather than Munich whenever schedules allow, since FRA's connection times to Luxembourg are more forgiving and the Lufthansa lounge network there is deeper, giving you a proper shower and meal before the final 45-minute puddle jump. Seasonally, this route rewards patience: January, February, March, October, and November consistently produce the softest business class fares, since Luxembourg's financial-sector travelers and EU institutional visitors cluster their trips outside those shoulder months. Arrive at Richmond International with normal domestic timing, but pad your connection window in Atlanta or JFK to at least two hours given the international transfer and occasional gate changes on Delta's widebody fleet.
Given the total absence of nonstop competition and the multiple viable routings through different hubs and carriers, fares on this corridor fluctuate more than travelers expect — which is exactly why setting up fare alerts for Richmond–Luxembourg business class, rather than checking manually, tends to catch the best windows before they close.