There's no nonstop path bridging San Jose's Mineta International with Valencia's compact Manises airport, which means every itinerary in business class from San Jose to Valencia funnels through a major transatlantic gateway — and after dozens of trips on this corridor, I can tell you the routing matters as much as the airline. The most reliable option pairs American Airlines' domestic or transcon metal into a hub like Dallas, Chicago, or Philadelphia with a transatlantic leg operated by British Airways or Iberia into Madrid, followed by a short regional hop down to Valencia. Total journey time hovers around 11.5 hours of actual flying, though with connections you should budget closer to 15-17 hours door to door.
My preference is routing through London on British Airways, where the Club Suite — with its sliding door and direct aisle access on the 777 and A350 fleet — makes the long transatlantic segment genuinely restful, then connecting onward via Iberia's A321 business class into Madrid before the final puddle-jump to Valencia. Iberia's own long-haul product, found on their A350s, has improved markedly in recent years with proper flat-bed seating in a reverse herringbone configuration, and if you can snag Iberia metal all the way from a US gateway like JFK or Miami into Madrid, you cut down on one connection entirely. Insider tip: build in at least a two-hour buffer in Madrid-Barajas, since Terminal 4S-to-T4 transfers for the Valencia connection can eat more time than posted minimum connection windows suggest, especially during morning arrival banks when immigration lines swell.
Shoulder season — April, May, September, and October — consistently delivers the best combination of fare value and pleasant Valencian weather, avoiding both summer's heat and premium pricing. Because award and premium cash fares on this route fluctuate significantly based on Iberia and British Airways scheduling changes through Madrid and London, setting up automated fare alerts is the smartest way to catch a business class fare worth booking before it disappears.