Seville rarely appears on nonstop route maps from the Pacific Northwest, and that's precisely what makes routing strategy the whole game when booking business class from Seattle to Seville. There is no direct service on this city pair, so every itinerary funnels through a major hub—typically London Heathrow via British Airways, or Madrid via Iberia, both drawing on their transatlantic joint-business partnership with American Airlines. The most reliable answer for travelers researching this route: expect a one-stop journey of roughly 11.5 hours total flight time, with British Airways' Club Suite (their reverse-herringbone seat with a closing door, rolled out across their 777 and 787 fleet) representing the strongest hard-product option on the transatlantic leg out of Seattle.
Having routed through both Heathrow and Madrid multiple times to reach Andalusia, I favor the Iberia connection when schedules allow—Madrid-Barajas Terminal 4 is a genuinely pleasant, light-filled hub with a short, well-signed connection to the Seville shuttle flights, and you avoid the security theater and long walks that come with Heathrow Terminal 5 transfers. If you do connect through London, budget extra time; T5's American Airlines and British Airways codeshare desks can queue up during peak summer afternoons. One insider tip worth knowing: Iberia's Madrid-Seville domestic hop is often ticketed in business class as a through-fare from Seattle, meaning you get lounge access and priority handling in Madrid even on that short 45-minute regional segment—a detail many travelers miss when they assume the "real" business class experience ends at the transatlantic gate.
Seasonally, April, May, September, and October are the sweet spots—not just for Seville's climate, which turns brutal by July, but because premium cabin award space and fare sales both loosen up outside peak summer demand. Given the routing complexity and multiple carrier combinations in play, setting up automated fare alerts for this specific city pair is the smartest way to catch the periodic drops on the American-Iberia-British Airways network before they disappear.