Poznan remains one of Europe's stubbornly under-served regional capitals, which means there's no nonstop option — every business class from Washington Reagan to Poznan itinerary routes through a major continental hub, typically Frankfurt, Munich, or Warsaw, before a short connecting hop on LOT Polish Airlines. The reality of this route is that DCA itself only handles a handful of transatlantic widebody departures, so United and Delta passengers usually route first through JFK, Newark, or Dulles before crossing the Atlantic, while LOT loyalists can sometimes build a same-day connection through Warsaw Chopin. Total elapsed time hovers around 9 hours of actual flying, but factor in a realistic 12-14 hour door-to-door journey once you account for the DCA-to-hub leg and the final Warsaw-Poznan or Munich-Poznan regional segment.
Having flown this corridor repeatedly, I'd steer travelers toward routings via Munich or Frankfurt on United or Lufthansa-operated codeshares when seat availability allows, since Star Alliance's central European hub infrastructure handles Poland connections more gracefully than most alternatives. Delta passengers connecting through Amsterdam or Paris on Air France-KLM metal will find comfortable long-haul business seats — Delta's own A330 and A350 One Suite product is a strong choice for the transatlantic leg — but the final regional connection to Poznan is always going to be a narrowbody affair, so don't expect lie-flat comfort on that last hop. My insider tip: build in a minimum 90-minute connection in Warsaw if routing through LOT, since immigration and security recheck for non-Schengen arrivals can eat into tight layovers more than posted minimum connection times suggest.
Seasonally, January through March and again in October and November tend to yield the softest fares, as Poznan's trade-fair calendar (notably the massive Poznań International Fair events) spikes demand and pricing in spring and early autumn, so business travelers with flexibility should target the shoulder months aggressively. Given how thin premium inventory can be on the connecting Poland legs, I'd recommend setting up automated fare tracking for this specific city pair rather than checking manually, since availability windows can open and close within days.