There's no nonstop path linking Palm Beach County to England's second city, which means every business class from West Palm Beach to Birmingham itinerary routes through a major American hub before crossing the Atlantic. In practice, that means American Airlines via Philadelphia or Charlotte into London Heathrow, Delta via Atlanta or JFK into Heathrow, or United via Newark or Washington Dulles—each carrier then requires a connection onward to Birmingham, either via a domestic British Airways or partner shuttle, or a rebooked rail transfer from Heathrow or Euston. American's Flagship Suite on its 777-300ER or A321neo transcon legs is a strong pick for the domestic segment, while Delta's One Suites on its A330-900 or A350 give you sliding doors and genuine privacy across the pond, and United's Polaris seats on the 767 or 787 remain a reliable, direct-aisle-access product for the long haul.
Having routed this trip more times than I can count, my advice is to treat the domestic-to-international connection as the trip's real chess match: build in at least two hours at your U.S. gateway, since a missed transatlantic segment from Charlotte or Atlanta can wreck an otherwise seamless business class experience. One insider trick: booking the final Birmingham leg as a separate low-cost or rail ticket rather than through the airline's connection engine often shaves hours off total journey time, since direct BHX flights from Heathrow are limited and rail into Birmingham New Street from Euston is frequently faster and more dependable than a same-day short-haul connection.
Seasonality matters more than people assume on this corridor—January, February, March, October, and November consistently offer the softest premium cabin demand, as Florida's snowbird season quiets down before spring and the UK's summer tourist surge hasn't yet begun. Given how these connecting itineraries fluctuate across three carriers and multiple hub combinations, setting up fare alerts is the smartest way to catch a premium seat before award space or discounted J fares disappear.