Seville remains one of Andalusia's most rewarding surprises, and reaching it in comfort requires a bit of strategic routing since there's no nonstop option from South Florida. The reality is that business class from West Palm Beach to Seville always involves a connection, typically through Madrid, London, or a major East Coast gateway, with total journey times running well beyond the 9.5-hour flying segment once you account for the transfer. American Airlines offers the most convenient positioning for PBI travelers, connecting through Miami or JFK onto joint-venture partner Iberia or British Airways, and this transatlantic alliance is precisely why savvy flyers should think of this route as a three-airline puzzle rather than a single-carrier itinerary.
Having flown this corridor repeatedly, I'd steer serious travelers toward routing via Madrid on Iberia, whose A330 and A350 business class cabins feature fully flat seats with direct aisle access on the A350 configuration—a meaningful upgrade over the older Iberia A330 herringbone layout, so it's worth checking your aircraft type at booking. The alternative path through London on British Airways puts you in their Club Suite on the transatlantic long-haul segment (found on 777s and A350s), which offers a sliding door and genuine privacy, though you'll then face a shorter regional hop down to Seville on a narrowbody with a more modest business product. My insider tip: build in a two-to-three hour connection window in Madrid rather than rushing, since Iberia's T4 satellite terminal transfers for international-to-domestic connections can require an extra security recheck that catches first-timers off guard.
Shoulder seasons—April, May, September, and October—consistently deliver the best combination of fare value and Andalusian weather, avoiding both the punishing summer heat and winter's thinner schedules. Because pricing on this three-airline, multi-hub route fluctuates based on which connection releases premium inventory first, setting up automated fare alerts is genuinely the smartest way to catch a well-priced business class seat before it disappears.