There's no nonstop path to Stuttgart from South Florida, which is precisely why the routing choice matters more than the marketing copy suggests. Business class from West Palm Beach to Stuttgart always involves a connection, and after dozens of trips on this corridor, I can tell you the smart money runs through Delta's JFK or Atlanta hub into Frankfurt or Munich with a short rail or puddle-jump into Stuttgart, or American's transatlantic gateway via Philadelphia or Charlotte into Frankfurt or Munich, with United routing through Newark or Washington Dulles. Total journey time typically lands near 9.5 hours of actual flight time, but factor in a solid 90 minutes to 2 hours for the connection if you're continuing onward by air rather than train, since Stuttgart itself only sees limited mainline widebody service.
The hardware varies meaningfully by carrier, and this is where experience pays off. Delta's A330-900neo and A350 fleets on the Atlanta-Frankfurt or JFK-Frankfurt legs offer the Delta One suite with a closing door, which I'd rank as the most restful option for this itinerary. American's 777-300ER and 787-9 aircraft on Philadelphia or Charlotte to Frankfurt runs feature the Flagship Suite on select 777s, though older 787 business seats without doors still show up on some rotations, so check your aircraft type before booking. United's polaris seats on the 767 and 787 fleets serving Newark-Frankfurt or Dulles-Munich are solid but tighter in the older cabins. My insider tip: if connecting through Frankfurt, use the short-haul feeder flights into Stuttgart rather than the train if your bags are checked through, since German rail strikes have stranded more than one business traveler mid-itinerary in recent winters.
January through March and October into November consistently produce the softest fares on this corridor, as Stuttgart's trade fair calendar and Oktoberfest overflow crowds thin out. Given the multi-airline, multi-hub complexity of this route, setting up automated fare alerts is the most efficient way to catch a premium cabin deal before it disappears.