Nuremberg's modest airport handles no widebody service from the United States, which means every seasoned traveler booking business class from Atlanta to Nuremberg accepts a connection as part of the itinerary—and the smart money routes through Frankfurt or Munich on Lufthansa rather than forcing an awkward Delta or United transfer through a secondary European gateway. Delta operates its solid A330 or A350 business class nonstop from Atlanta to Frankfurt, with flat-bed seats and Delta One suites on select aircraft, then hands you to a Lufthansa regional jet for the short hop into Nuremberg. Lufthansa itself, via its own Frankfurt or Munich hubs, increasingly offers Allegris business class on select long-haul routes, though you'll want to confirm aircraft type at booking since older 747-8 and A340 configurations still fly parts of the Atlanta network. United routes through Newark or Washington Dulles with Polaris business class, a strong option if your schedule favors an East Coast repositioning before the transatlantic leg.
Having flown this connection repeatedly, my advice is to build in at least 90 minutes in Frankfurt or Munich rather than the standard 60—German immigration and the walk to regional gates eats time, and missing your Nuremberg connector strands you overnight far more often than travelers expect. Munich is the more pleasant hub for this itinerary: Lufthansa's home turf means better rebooking flexibility and access to the excellent Lufthansa Business Lounge network if you're delayed. An insider trick few mention: flying into Munich rather than Frankfurt and taking the train to Nuremberg (just over an hour on the ICE) is often faster door-to-door than waiting for a connecting flight, and it lets you bank miles on the long-haul segment while sidestepping regional flight cancellations that plague winter schedules.
January through March and October into November consistently bring softer fares on this corridor, as Bavaria's trade fair calendar—particularly the Nuremberg Toy Fair in late January—creates pockets of both elevated demand and unexpected award availability depending on how airlines release inventory. Given how much fare movement happens on connecting itineraries like this one, setting up automated price tracking for the Atlanta-Nuremberg corridor is the most reliable way to catch the right combination of fare and routing before it disappears.