Nuremberg's modest airport, tucked into Bavaria's industrial heartland, has never had the connectivity to justify a nonstop from the Mid-Atlantic, which means every seasoned traveler booking business class from Baltimore to Nuremberg is really booking a connection strategy first and a cabin second. There is no direct service on this pairing; the practical answer is routing through Frankfurt or Munich on Lufthansa, or via a Delta/American joint-venture partner hub. Lufthansa's Frankfurt bank of flights aligns beautifully with the short Nuremberg hop, and depending on your original BWI departure, you'll either be aboard a Lufthansa long-haul jet with the airline's newer Allegris business suite (still rolling out fleet-wide, so it's worth checking your aircraft type before booking) or the tried-and-true fully flat seat on older 747-8s and A340s. American and Delta typically route you through their own transatlantic gateways—Philadelphia or JFK for American connecting onto British Airways or Finnair-style partners isn't relevant here, but Delta's joint venture with Lufthansa Group often books you onto a codeshare metal that's operationally Lufthansa.
My longstanding tip: when connecting through Frankfurt, budget extra buffer time even with a confirmed short layover, since FRA's passport control and the walk between concourses can eat forty-five minutes that don't show up on paper. Munich, by contrast, is a gentler connection with shorter walks and better lounge access if your itinerary allows choosing between the two hubs—ask your booking agent or check both routings before locking in.
Seasonality here rewards patience: January through March and again in October and November are historically the softest months for premium fares into Bavaria, as the trade fair calendar (Nuremberg's toy fair aside) creates less business-travel pressure than summer. Given the volatility of transatlantic business fares and the frequent repricing around Lufthansa's Frankfurt and Munich banks, setting up automated fare alerts for this specific city pair is the smartest way to catch a premium-cabin fare drop before it disappears.