There is no nonstop path linking these two airports, so business class from Baltimore to Mykonos always involves at least one strategic hub connection, and that reality shapes everything about how this journey should be booked. The most reliable routing runs through London Heathrow on British Airways, connecting onward to Athens or occasionally direct into Mykonos during peak summer months, or through Munich or Frankfurt via Lufthansa before dropping into Athens for a short Aegean Airlines hop to the island. British Airways deploys its Club Suite on the transatlantic BWI-to-Heathrow segment on select aircraft, delivering a proper door and fully flat bed, while Lufthansa's long-haul equipment increasingly features the new Allegris cabin, though older 747 and A330 configurations still appear on some rotations, so it's worth checking the specific aircraft when booking.
The real craft in this itinerary is treating the final leg into Mykonos as its own puzzle. Aegean Airlines operates the Athens-to-Mykonos hop, and while it's typically a short regional flight without a dedicated premium cabin in the way transatlantic passengers expect, booking it in tandem with your long-haul business class ticket rather than separately often preserves baggage protection and rebooking flexibility if weather or strikes disrupt Athens connections, which happens more often than travelers expect in shoulder season. My insider tip: fly into Athens with enough buffer, at least three hours, to clear immigration and recheck bags for the Olympic Air or Aegean connection, since Athens International's transfer process for non-Schengen arrivals can eat more time than seasoned Europe travelers anticipate.
April, May, September, and October remain the sweet spot for this journey, not just for cooler, less crowded conditions in Mykonos but because premium fares from Baltimore into the Athens gateway tend to soften once peak July-August demand fades. Given the multiple carrier and routing permutations at play here, setting up fare alerts for the BWI-Athens-Mykonos combination is genuinely the smartest move, since award and paid business class space fluctuates unpredictably across British Airways, Lufthansa, and Aegean depending on the week you search.