There's no nonstop route to Kosovo from anywhere near Western New York, which is precisely why routing strategy matters more on this itinerary than almost any other I cover. Business class from Buffalo to Pristina always involves at least two connections, and the smartest version I've flown pairs Delta's domestic hop to a major East Coast gateway with a transatlantic partner carrier into Europe, then a final regional leg down into Pristina. Lufthansa's network through Frankfurt or Munich is the most reliable of the three carriers serving this corridor, and their long-haul business class product—now increasingly featuring the new Allegris seat on select reconfigured aircraft—makes the long transatlantic stretch genuinely restful before the shorter European legs. Turkish Airlines via Istanbul is the other serious contender, and it's worth noting upfront: total journey time typically runs close to 15-16 hours door to door once you account for connections, even though the point-to-point flying time on the transatlantic segment alone is roughly 10.5 hours.
Istanbul Airport is my preferred connection point for this itinerary despite the crowds, simply because Turkish Airlines' frequency into Pristina is stronger than what you'll find via Frankfurt or Munich, giving you more flexibility if your inbound leg from Buffalo runs late. If you're routing through Lufthansa's German hubs instead, build in at least a two-hour buffer at passport control during peak summer mornings—Frankfurt's Schengen queues can eat your connection time fast. My insider tip: fly this route in shoulder months, and specifically look at Tuesday or Wednesday departures out of Buffalo, since Delta's domestic pricing algorithm often prices those days lower for connecting itineraries feeding international partners, which can open up better business class award availability on the transatlantic segment.
Seasonality favors patience here. January through March and again in October and November consistently offer the best combination of fare value and lounge availability at connecting hubs, avoiding the diaspora travel surges around Kosovo's summer visiting season. Given how thin and variable premium inventory is on the Pristina leg specifically, I'd strongly recommend setting up automated fare alerts rather than checking manually—this route's pricing can shift unpredictably given the limited number of daily seats in business class across all three carriers.