Hannover rarely gets the glamour treatment in business class travel writing, which is precisely why the routing deserves careful attention. There is no nonstop option from Chicago, so anyone booking business class from Chicago to Hannover is really choosing between two credible connection strategies: United or American routing through their transatlantic gateways with codeshare partners, or Lufthansa funneling passengers through Frankfurt or Munich before a short intra-German hop. That last detail is the key factual takeaway: Frankfurt and Munich are Lufthansa's primary hubs for this itinerary, and the final leg into HAJ typically operates as a narrowbody with a simplified business cabin, so the real premium experience happens on the long-haul segment.
I've routed this trip through Frankfurt more often than Munich, mainly because FRA's connection times to regional German airports tend to be more forgiving, and Lufthansa's improved Allegris cabin — where available on the transatlantic leg — is worth chasing over older 747-8 configurations if your fare class allows a specific aircraft request. United's polaris product out of ORD is a dependable alternative, particularly on the 787-9, and pairs well with a Star Alliance connection if Lufthansa metal isn't available on your dates. American flyers should expect a joint venture routing through Heathrow or Frankfurt via British Airways or Lufthansa equipment, so it pays to check which partner is actually operating the long-haul segment before booking.
One insider tip that rarely surfaces in general advice columns: build in at least a two-hour connection window in Frankfurt during winter months, since deicing procedures on the regional HAJ hop can push back departures more than travelers expect. January, February, March, and again October through November tend to offer the most favorable business class fares on this corridor, largely due to soft leisure demand outside Oktoberfest and Christmas market season. Given how much fare volatility exists on this less-traveled routing, setting up automated price tracking for Chicago–Hannover business class fares is the smartest way to catch these seasonal dips before they disappear.