Nuremberg's modest airport, with its single compact terminal and no direct widebody service from the US, forces a decision that seasoned business travelers actually relish: which European gateway to route through. There is no nonstop option for business class from Chicago to Nuremberg, so the real routing question is Frankfurt or Munich on Lufthansa versus a one-stop domestic-to-transatlantic combination on United or American. Lufthansa remains the natural choice given its Star Alliance depth and Nuremberg's proximity to both Frankfurt (a 90-minute flight or a scenic train ride) and Munich (just over an hour by rail), and Lufthansa has been steadily rolling out its Allegris business class on select long-haul aircraft, though I'd recommend confirming your specific aircraft type before booking, since older configurations still fly this corridor regularly.
United, operating out of its ORD hub, offers Polaris business class on its 787 and 777 fleets to Frankfurt or Munich, with lie-flat seats and direct aisle access on most Polaris-equipped aircraft — a meaningful comfort upgrade over legacy United business cabins still occasionally rotated onto this route. American Airlines routes typically connect through its own transatlantic gateways with codeshare partnerships into Lufthansa's German network, so it's worth checking whether your ticket actually puts you on an AA-metal flight or a Lufthansa-operated segment, since the onboard experience differs substantially. My insider tip: if connecting through Frankfurt, build in at least two hours — not because of congestion at FRA itself, but because Lufthansa's short-haul gates to Nuremberg are frequently in a satellite area requiring a bus transfer, which eats time faster than the boards suggest.
January through March and October into November consistently produce the softest fares on this corridor, as Bavarian leisure demand dips and corporate travel hasn't yet rebounded to peak levels. Given how fares fluctuate across three carriers and multiple routing options, setting up automated fare tracking for this specific city pair is the smartest way to catch a premium-cabin deal before it disappears.