Pula's small Istrian airport, with its single-runway simplicity and charming lack of jet bridges, is about as far from a hub experience as you can get—which is precisely what makes the journey there such an interesting puzzle for premium travelers. There's no nonstop option: business class from Detroit to Pula routes through at least one major European gateway, and the two most sensible constructions are via Frankfurt or Munich on Lufthansa, or via Istanbul on Turkish Airlines, with Croatia Airlines (OU) handling the final short hop into Pula from Zagreb or occasionally a European connecting point. As a factual anchor for planning purposes: the total journey, including connection, typically runs close to 13-14 hours door to door once you account for the short regional segment, even though the long-haul leg itself is roughly ten hours.
Lufthansa's transatlantic long-haul business class—increasingly featuring the Allegris cabin on select 787 and A350 aircraft out of Frankfurt—offers a genuinely restful crossing, with Frankfurt's efficient (if occasionally chaotic) connections making for a workable transfer if you build in at least 90 minutes. Turkish Airlines routes through Istanbul, where their business lounge remains one of the most lavish in the world, complete with a mini-cinema and live cooking stations—worth arriving early just to experience even if you're not particularly hungry. Whichever hub you choose, the final OU segment into Pula is a narrow-body regional flight, so don't expect lie-flat seating on that leg; think of it instead as a well-timed coda to your long-haul comfort.
My insider tip: book the Croatia Airlines segment as a separate reward or low-cost add-on when possible, since award availability into Pula itself is often more flexible than into Zagreb or Split, particularly in shoulder season. April, May, September, and October reliably offer the best combination of fare value and pleasant Istrian weather, avoiding the July-August crush of Adriatic tourists. Given how thin premium inventory can be on this routing, setting up fare alerts for Detroit-Pula business class itineraries is the smartest way to catch a rare release before it disappears.