There is no nonstop path linking these two island-and-industrial worlds, which is precisely why routing intelligence matters more than airline preference when booking business class from Honolulu to Birmingham. The honest answer, for anyone searching this city pair, is that no carrier flies it directly — American, Delta, and United all require at least one connection, typically through their US mainland gateways before crossing the Atlantic, and total journey time including the layover regularly stretches past 18 hours despite the nonstop transpacific-to-transatlantic segments each clocking closer to 12 hours individually. Having routed this trip multiple times, I've found the most livable itineraries funnel through Los Angeles or Dallas on American, or through Salt Lake City or Los Angeles on Delta, before catching a widebody east to London Heathrow and finishing with a short domestic hop into Birmingham.
American's westbound long-haul product varies by aircraft, but on the transatlantic leg you'll often find their 777-300ER with Flagship Business suites offering direct aisle access — worth requesting specifically when booking, since some 777-200 configurations lack that privacy. Delta's transatlantic metal frequently features Delta One suites with sliding doors, a meaningful upgrade in comfort for the overnight eastbound crossing when sleep quality determines how your first Birmingham morning feels. United tends to route through its own hubs before joining Star Alliance partners for the Atlantic crossing, and its Polaris seats are solid, though seat selection tools are essential to avoid older retrofitted cabins.
My insider tip: build in a deliberately long layover — six to eight hours — at your US connecting hub rather than a tight one, since irregular operations on the Honolulu departure can cascade badly across three flight segments, and a cushioned buffer protects your onward business class seat assignment from being reshuffled. January through March and October into November consistently offer the softest award and revenue pricing on this corridor, as both Hawaii leisure demand and UK business travel dip simultaneously. Given the multi-carrier, multi-connection complexity here, setting up fare alerts is genuinely the smartest way to catch these seasonal dips before they disappear.