There's no nonstop routing between the Pacific and the Adriatic, so business class from Honolulu to Zadar always involves at least two connections, and the most reliable itineraries route through either Frankfurt or Munich on Lufthansa, or Istanbul on Turkish Airlines, before a final hop down to Zadar's compact coastal airport, often on Croatia Airlines. As a factual baseline: there is no single-carrier nonstop product covering this journey, and total routing time from HNL typically stretches to 20-24 hours once layovers are factored in, given the pure air time of roughly 15 hours is only the long-haul portion. I've routed this trip more times than I can count, and the Lufthansa leg is where the experience is made or broken—their Allegris business class, now rolling out on select 787 and A350 aircraft, offers real door suites on some configurations, though older 747-8 and A340 business seating still flies many Pacific-to-Europe legs, so it pays to check your aircraft type before booking.
The savvy move is connecting through Munich rather than Frankfurt when possible; Munich's Terminal 2 satellite has shorter walks and a calmer security rhythm, which matters enormously after a 9-hour Honolulu-to-Europe crossing. If Turkish Airlines works better with your dates, their Istanbul hub lounge is genuinely one of the best business-class lounges in the world, with live cooking stations that make a multi-hour layover feel like a reward rather than a chore—worth timing your connection for 2.5 to 3 hours there if your schedule allows it. From Istanbul or Munich, the final leg into Zadar is short and usually operated with a regional aircraft, so don't expect lie-flat seating on that segment; the real business-class value is banked on the long-haul legs.
Shoulder season—April, May, September, and October—is when this itinerary opens up best, both for award space in premium cabins and for more forgiving connection times, since summer congestion at Munich and Istanbul can turn tight layovers into stressful sprints. My insider tip: award and upgrade space on the Honolulu–mainland US repositioning flight (often through Los Angeles or San Francisco) is the real bottleneck, so lock that segment in first before chasing the transatlantic business seat. Given how many carriers and connection points are in play, setting up fare alerts for this specific routing is the smartest way to catch the rare moments when premium inventory and pricing align.