Reykjavík has quietly become one of the more logistically interesting business class puzzles for Midwest travelers, and after routing through this corridor more times than I can count, I can say definitively: there is no nonstop business class from Indianapolis to Reykjavík. Icelandair does not serve IND directly, which means every Indianapolis to Reykjavík business class itinerary requires a connection, typically through Delta's Atlanta or Minneapolis-St. Paul hubs, or through United's Newark or Chicago O'Hare gateways, with Icelandair itself sometimes picked up as the transatlantic leg via a codeshare or separate ticket through JFK or Boston. Delta's Atlanta connection tends to be the smoothest for Hoosier travelers, since IND has multiple daily mainline flights to ATL, allowing a comfortable buffer before boarding a Delta One flight across the Atlantic.
The transatlantic segment is where the real decision-making happens. Delta One suites, with their sliding privacy doors, appear on many of the widebody aircraft rotated onto European runs, while United's Polaris seats, redesigned with direct aisle access on most retrofitted 767s and 777s, offer a similarly strong lie-flat experience out of Newark. If your connection routes you toward Icelandair metal for the final KEF hop, know that Icelandair's business class is a modest, recliner-style product rather than a suite — perfectly fine for the shorter Atlantic crossing but not the star of the journey. My insider tip: because Keflavík airport is compact and efficient, even connections with tighter layovers of 70-90 minutes are workable if you're arriving on a widebody with priority disembarkation, which saves valuable time during Iceland's brief but glorious summer daylight window.
Late spring through early autumn — May through September — brings both the best weather for Iceland excursions and, counterintuitively, some of the more attainable premium cabin availability, as airlines add capacity to meet leisure demand. Award space and last-minute upgrades fluctuate constantly on this connecting itinerary, so setting up fare alerts across Delta, United, and Icelandair pricing is the smartest way to catch a favorable opening before it disappears.