There's no nonstop path linking the Mississippi Delta to the Algarve coast, which means booking business class from Memphis to Faro is fundamentally an exercise in routing strategy rather than simple point-to-point shopping. The most reliable itineraries funnel through Atlanta on Delta before crossing the Atlantic, or route via London or Lisbon on British Airways and TAP Air Portugal respectively. Delta's transatlantic widebodies out of Atlanta typically feature Delta One suites with sliding doors on select aircraft, giving Memphis travelers a genuinely premium start to the journey before connecting onward to Faro on a regional partner or continuing through a European gateway. For those routing via London, British Airways' Club Suite—with its direct aisle access and privacy door—makes the long-haul leg from Atlanta or JFK feel far shorter than the ~9 hours suggests, though the final hop to Faro is typically operated as a short-haul flight in a recliner-style business cabin.
My preferred routing, after flying this corridor repeatedly, is via Lisbon on TAP Air Portugal. TAP's transatlantic business class, while not flashy, offers lie-flat comfort and the advantage of landing in Lisbon with easy same-terminal connections to Faro on regional TAP flights—Lisbon's airport is compact enough that even tight layovers rarely feel stressful. Insider tip: build in a two-hour layover minimum in Lisbon during summer, when Iberian air traffic control delays are common, but during shoulder season you can comfortably work with 90 minutes. Atlanta remains the more dependable hub if your priority is minimizing connections and maximizing lounge access, since Delta's Sky Club network there is far more extensive than what you'll find overseas.
April, May, September, and October consistently deliver the best value on this corridor, as Algarve tourism surges in peak summer and winter is thin on premium demand, softening fares in the shoulders. Given the complexity of routing options and the volatility of transatlantic business fares tied to fuel surcharges and seasonal capacity shifts, setting up automated fare alerts for this specific city pair is the smartest way to catch a premium seat before prices firm up.