Nuremberg rarely appears on the radar of premium travelers departing the Bay Area, which is precisely why it rewards those willing to plan carefully. There is no nonstop option: business class from Oakland to Nuremberg always routes through a major hub, typically Delta via Amsterdam or Atlanta, United via Chicago, Denver, or Newark, or American via a connection through Philadelphia, Chicago, or a European gateway like Frankfurt. All three carriers price this as a single through-fare despite the connection, and the total journey generally runs in the 14 to 16 hour range once you factor in the layover, against a raw air time of roughly 11.5 hours point-to-point. Delta's transatlantic legs on this itinerary are often flown with Delta One suites featuring sliding doors on widebody aircraft, while United's international business product, Polaris, offers lie-flat seating with direct aisle access on most of its European-bound widebodies. American's Flagship Business, found on its 777 and 787 fleets, rounds out the third viable option.
My strong preference on this routing is Amsterdam as the connecting hub over the domestic US hubs — Schiphol's transfer process is fast, the Delta SkyClub-affiliated KLM Crown Lounges are excellent for a shower and reset, and the short intra-European hop down to Nuremberg is usually operated on a comfortable narrowbody with minimal congestion. If connecting domestically instead, build in extra buffer time at Chicago O'Hare or Newark during winter months, when de-icing delays are common and can cascade into missed connections onto the transatlantic leg.
Deal-wise, this Bavarian route rewards patience: January, February, March, October, and November consistently produce the softest business class fares, since Nuremberg's tourist and trade-show traffic (notably Toy Fair in late January and Christkindlesmarkt in December) creates uneven demand patterns that airlines misprice in the shoulder months. Given the three-carrier competition and hub variability, setting up automated fare alerts for this specific city pair is the smartest way to catch a mispriced Delta One or Polaris fare before it disappears.