Omaha isn't a market where transatlantic business class gets discussed often, but after routing through this corridor a dozen times, I can tell you the connections matter more than the mileage. There is no nonstop option, so business class from Omaha to Valencia inevitably means building an itinerary through a major hub — and the two that work best are Chicago O'Hare via American Airlines or London Heathrow via British Airways. American's domestic leg from OMA feeds into O'Hare, where you can pick up a widebody with American's Flagship Business seats to Madrid or London before connecting onward to Valencia on a regional partner. Alternatively, routing through Heathrow on British Airways puts you in their Club Suite — a fully enclosed, direct-aisle-access seat introduced on their 777s and A350s — for the long Atlantic crossing, with Iberia often handling the short Madrid-to-Valencia or London-to-Valencia connection in a domestic business cabin.
My preference, after testing both, is the Heathrow routing. Club Suite's privacy and BA's Terminal 5 connections tend to be smoother than O'Hare's often-congested international transfers, and Iberia's short-haul business product, while modest, gets the job done for the final hop. One insider tip worth noting: Iberia occasionally prices Madrid-Valencia as a domestic add-on that's cheaper booked separately in economy rather than bundled into the long-haul business fare — a quirk that's saved me money without sacrificing comfort on the ten-hour transatlantic segment, where the real value lives anyway.
Seasonality plays a real role here. April, May, September, and October consistently offer the best combination of fare value and pleasant Valencia weather, avoiding both the deep-summer heat and the premium pricing that comes with peak European travel months. Because fares on this Omaha-to-Valencia corridor shift frequently depending on which hub and carrier combination is running promotions, setting up automated fare alerts is the smartest way to catch a business class fare drop before it disappears.