There's no nonstop way to leapfrog from the Texas Hill Country to the Ionian coast, which is precisely what makes routing strategy the most important decision you'll make when booking business class from San Antonio to Corfu. In practice, this means connecting through a major European gateway, and the two smartest options are Lufthansa via Frankfurt or Munich, or British Airways via London Heathrow, with Aegean Airlines picking up the final short hop into Corfu's compact CFU airport during the warmer months. Factually speaking: total journey time typically runs close to 12 hours of flying, split across a long transatlantic leg and a shorter European connector, since Corfu has no long-haul widebody service of its own.
I've flown this corridor enough times to have a strong preference for the Lufthansa routing when their Allegris cabin is on the transatlantic segment—it's their newest long-haul business product, with a proper door and more privacy than the older flat-bed seats still flying on some Frankfurt and Munich rotations, so it's worth checking your aircraft type before booking. British Airways loyalists will find the Club Suite, with its sliding door and direct aisle access, a genuinely restful way to cross the Atlantic out of Heathrow, and Terminal 5's connections to European short-haul are efficient if your layover is tight. The Aegean leg itself is typically operated with a business cabin that's more about comfortable service and Greek hospitality than lie-flat hardware, so treat it as a pleasant coda rather than the main event. My insider tip: fly into Corfu on the earliest Aegean connection you can find, since afternoon arrivals in high summer coincide with charter traffic that clogs the tiny arrivals hall.
Seasonality matters enormously here—Corfu's tourist infrastructure and flight frequency swell from May through September, but the shoulder months of April, May, September, and October consistently offer the best combination of fare value and pleasant weather, with October especially rewarding for late-season warmth minus the crowds. Given how much fares fluctuate across these three carriers and their shifting connection banks, setting up automated fare tracking for this specific city pair is the most reliable way to catch a business class fare worth booking.