Corfu's turquoise coastline and Venetian old town reward the patient traveler, and patience is exactly what's required here, since there's no nonstop option for business class from San Diego to Corfu — every itinerary routes through a European or transatlantic hub, with total journey time running well beyond the 13.5-hour flying segment once you factor in connections. British Airways offers the most logical routing for West Coast flyers, positioning you through London Heathrow with a same-day connection onto Aegean Airlines or a British Airways seasonal service into CFU; Lufthansa funnels traffic through Frankfurt or Munich with excellent onward Star Alliance connectivity via Aegean's Athens hub; and Aegean itself, as Greece's flag carrier, provides the most culturally attuned final-leg experience once you've crossed the Atlantic.
Having routed through all three carriers repeatedly, I'd steer discerning travelers toward British Airways' Club Suite on the transatlantic long-haul segment — the fully enclosed suite with a closing door is a meaningful upgrade over the older Club World cabin still found on some Lufthansa long-haul aircraft, though Lufthansa's newer Allegris cabin, where deployed, competes well with its suite-style seating and superior wine list curated by German sommeliers. My insider tip: book the Frankfurt-to-Athens-to-Corfu triple-connection only if your layover in Frankfurt exceeds 90 minutes, since Terminal 1's passport control queues balloon during peak summer months and have caused missed connections even for business class passengers using priority lanes.
Shoulder season — April, May, September, and October — is when this route rewards flexibility most, as Corfu's tourist crush eases, Aegean adds capacity for the Greek diaspora's autumn visits, and premium cabin award space opens up on both Lufthansa and British Airways metal. Given the multi-carrier complexity and fluctuating award availability, setting up automated fare and mileage alerts for this specific SAN–CFU routing is the smartest way to catch the rare moments when premium inventory and reasonable positioning align.