Vilnius remains one of Europe's quieter capitals for premium American travelers, which is precisely what makes routing business class from West Palm Beach to Vilnius such a rewarding exercise in itinerary construction. There is no nonstop option here — nor will there be one anytime soon — so the real decision is which US carrier and which European gateway you trust to connect you onward. Fact worth noting: all three major US carriers serving this corridor (American, Delta, United) route passengers through their transatlantic hubs before a connecting flight into VNO, since Vilnius simply doesn't generate enough premium demand to justify widebody service. From PBI, that typically means a domestic hop or positioning flight to a hub like Miami, JFK, Newark, or Boston before the long-haul jump.
My preference after years flying this corridor is United through Newark, where Polaris business class on the 767 or 777 gives you lie-flat comfort and Newark's renovated Terminal C makes the connection painless if you build in at least 90 minutes. Delta's One Suite product out of JFK is arguably the best hard product of the three domestically, particularly on the A330-900 or A350, and Delta's partnership with Air Baltic or LOT (via Star Alliance-adjacent codeshares through partners) can smooth the final leg into Vilnius. American's routing tends to funnel through London Heathrow or occasionally Helsinki via partner metal, and Flagship Suite on the 777-300ER is worth chasing if your dates align. The insider move locals don't advertise: book the transatlantic leg on points through a European hub with a long layover, then treat that city as a free stopover — Helsinki and Warsaw both make excellent one-night breaks before the short regional flight completes your journey.
Summer, especially June through August, brings the best award and cash availability for this itinerary, largely because Baltic leisure demand peaks and airlines add capacity on connecting European regional routes. Shoulder months like May and September often reward patient searchers with better business class saver space. Given how thin and volatile premium inventory can be on these connecting itineraries, setting up fare and award alerts specifically for the West Palm Beach to Vilnius business class routing will save you from watching prices swing without notice.