Croatia's capital rewards patience, and there is no nonstop path to it from South Florida that doesn't involve a thoughtful connection. There is, in fact, no direct business class from Fort Lauderdale to Zagreb, so the routing decision becomes the whole game: Delta passengers typically transit Amsterdam or Paris before a Croatia Airlines or partner hop onward, while Lufthansa loyalists route through Frankfurt or Munich, feeding into a Star Alliance connection with Croatia Airlines (OU) for the final short leg into ZAG. The transatlantic segment is where the real seat matters — Delta One suites on widebody aircraft out of FLL, or Lufthansa's long-haul business class (increasingly Allegris-configured on select routes) via its German hubs, both deliver a lie-flat foundation for the roughly 10.5-hour crossing before the shorter European connector.
My own routing preference has become Lufthansa via Munich rather than Frankfurt when the schedule allows it — Munich's connections to Zagreb tend to run through smaller, calmer gate areas with faster passport control, which matters enormously after an overnight transatlantic flight when you're trying to preserve a connection under two hours. If Delta is your carrier, Amsterdam's Schiphol offers a smoother Star-to-SkyTeam-adjacent transfer experience than Paris CDG, where terminal changes can eat into tight buffers; I always build at least 90 minutes into any CDG connection on this itinerary. Croatia Airlines' final leg is a narrowbody regional product, so don't expect lie-flat seating on that segment — the value of your business class fare is really concentrated in the transatlantic core, and travelers should mentally budget the short intra-European hop as a business-class-in-name-only convenience rather than a luxury experience.
Seasonality favors the shoulder months heavily here: January, February, and March see soft demand into Central Europe, while October and November catch the tail end of Adriatic tourism before winter sets in, both windows historically producing the most attractive business class fares on this corridor. Because pricing on connecting itineraries through Amsterdam, Frankfurt, Munich, or Paris can shift quickly with fuel surcharges and seasonal capacity changes, setting up automated fare alerts for the Fort Lauderdale–Zagreb corridor is the smartest way to catch a favorable fare before it disappears.