There's something fitting about a route connecting two cities built on leisure and reinvention, and after flying this corridor more times than I can count, I can say definitively: there is no nonstop option, so business class from Las Vegas to Alicante always involves a strategic connection, most reliably through London Heathrow on British Airways or Madrid/Chicago/Dallas via American Airlines codeshares with Iberia. The most consistent routing pairs American Airlines out of McCarran to a major East Coast or transatlantic gateway, then transfers onto a British Airways or Iberia long-haul segment into ALC or, more commonly, into Madrid with a short connecting hop, since Alicante itself doesn't see widescale widebody business class service. Total journey time hovers near 14-16 hours door-to-door once you factor connections, even though the transatlantic leg itself runs about 10.5 hours.
The real strategic decision is which carrier's hard product you want for that long Atlantic crossing. British Airways' Club Suite, now rolled out across much of their 777 and A350 fleet at Heathrow, gives you a direct-aisle-access door and genuine privacy, a meaningful upgrade over their older Club World cabins still flying on some 777s and 787s—so if you're booking BA metal, check the aircraft type before committing. Iberia's A330 and A350 business class, with its increasingly refined Spanish-inflected catering and lie-flat seats, feels like a fitting entrée into the country, especially if you route through Madrid and let a quick domestic-style hop deliver you into Alicante's manageable, low-stress airport. My insider tip: build in a two-hour minimum connection at Heathrow's Terminal 5 or Madrid Barajas Terminal 4S if you're transferring between American and its joint-business partners, since T5-to-T5 and T4S transfers are notably smoother than at hub airports where you'd need to reclear security.
Deal-wise, April, May, September, and October reward patience, when Costa Blanca demand softens and premium inventory opens up on the BA and Iberia sides. Given how much these fares swing on this specific corridor, setting up automated fare alerts is genuinely the smartest move you can make before booking.