Nuremberg's modest little airport, tucked into Bavaria's industrial heartland, doesn't get nonstop widebody service from anywhere in America—and that reality shapes every good business class from Los Angeles to Nuremberg itinerary I've built over the years. The practical truth: there is no direct option, so travelers connect through a major European or East Coast hub, typically via Frankfurt, Munich, or occasionally through a Delta partner gateway, before catching a short regional hop into NUE. American Airlines routes passengers through its transatlantic partners with connections in London or Frankfurt, Delta's strongest play is a one-stop through its own JFK or Atlanta hub paired with European partner metal, and United typically funnels LA travelers through Newark or Chicago before a Star Alliance connection deep into Bavaria. The long-haul segment out of LAX—roughly 11.5 hours to a European gateway—is where you want to spend your miles and preference, since the final leg into Nuremberg is invariably a narrowbody regional aircraft with no lie-flat product at all.
Having flown this corridor repeatedly, my advice is to prioritize your outbound long-haul cabin selection over obsessing about the short connector. United's Polaris business class on its 787 or 777 fleet out of LAX offers genuinely restful lie-flat suites with direct aisle access on most configurations, while Delta One suites, when scheduled on the transatlantic segment, deliver similarly excellent doors-and-privacy. American's Flagship Business, particularly on 777-300ER routings with Club World-style suites, rounds out the trio nicely. My insider tip: build in a three-hour buffer in Frankfurt or Munich rather than the standard connection window—German immigration and the walk to regional gates can eat more time than posted, especially during winter fog delays that affect Bavarian airports from December through February.
January through March and October into November remain the sweet spots for this routing, both for fare value and for avoiding the summer congestion that clogs Frankfurt and Munich's connecting banks. Because pricing on this three-airline, multi-hub route fluctuates constantly with seasonal demand and partner award space, setting up automated fare alerts is the smartest way to catch a premium-cabin opening before it disappears.